Regulatory Status
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Safety Data
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Expert Verdict
Antimicrobial peptide requiring regulatory clarification: if exerting preservative effect in finished product, EU Regulation 1223/2009 Article 14 may require listing in Annex V. Non-preservative antimicrobial use (e.g., skin microbiome modulation) requires clear documentation. Risk of microbiome disruption and resistance development warranted consideration.
Frequently Asked Questions
Is Heptapeptide-53 Amide safe in cosmetics?
Antimicrobial peptide requiring regulatory clarification: if exerting preservative effect in finished product, EU Regulation 1223/2009 Article 14 may require listing in Annex V. Non-preservative antimicrobial use (e.g., skin microbiome modulation) requires clear documentation. Risk of microbiome disruption and resistance development warranted consideration. The EU classifies Heptapeptide-53 Amide as "permitted". Safety rating: MODERATE.
Is Heptapeptide-53 Amide allowed in the EU?
Heptapeptide-53 Amide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Heptapeptide-53 Amide do in cosmetics?
Heptapeptide-53 Amide functions as: Antimicrobial (per CosIng function classification). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned / not publicly available.
What is the Margin of Safety for Heptapeptide-53 Amide?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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