Hexacarboxymethyl Dipeptide-12

INCI: HEXACARBOXYMETHYL DIPEPTIDE-12

CAS Number
1414380-75-8
Function
Humectant, skin conditioning, autophagy activator, NMF precursor
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Sodium salt form (heptasodium, CAS 1894171-13-1) is the commercially supplied version; supplier toxicological package should include RIPT, cytotoxicity, and ocular irritation data; no SCCS opinion available.

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Concern Level: Moderate

Frequently Asked Questions

Is Hexacarboxymethyl Dipeptide-12 safe in cosmetics?

Sodium salt form (heptasodium, CAS 1894171-13-1) is the commercially supplied version; supplier toxicological package should include RIPT, cytotoxicity, and ocular irritation data; no SCCS opinion available. The EU classifies Hexacarboxymethyl Dipeptide-12 as "permitted". Safety rating: GOOD.

Is Hexacarboxymethyl Dipeptide-12 allowed in the EU?

Hexacarboxymethyl Dipeptide-12 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hexacarboxymethyl Dipeptide-12 do in cosmetics?

Hexacarboxymethyl Dipeptide-12 functions as: Humectant, skin conditioning, autophagy activator, NMF precursor. It is classified as a cosmetic ingredient in our database. CAS number: 1414380-75-8.

What is the Margin of Safety for Hexacarboxymethyl Dipeptide-12?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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