Is HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE safe in cosmetics?
HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE has a safety rating of "GOOD" in our database. EU status: permitted.
Good
Cosmetic Ingredient
HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE
Also known as: Isolongifolene (2H-2,4a-Methanonaphthalene, 1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-, (2S,4aR)-), EINECS 214-494-2, Isolongifolene, iso-Longifolene, 2H-2,4a-Methanonaphthalene, 1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-
HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE (CAS 1135-66-6) is a cosmetic cosmetic ingredient functioning as Perfuming. NOAEL 1125 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 1135-66-6 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE is classified GHS Danger (H304) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Perfuming
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(1R,8S)-2,2,7,7-tetramethyltricyclo[6.2.1.01,6]undec-5-ene
InChIKey
CQUAYTJDLQBXCQ-NHYWBVRUSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE.
Regulatory Flags
cosing-sourced
eu-permitted
fragrance
needs-enrichment
ifra_fragrance
Known Synonyms
Isolongifolene (2H-2,4a-Methanonaphthalene, 1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-, (2S,4aR)-)
EINECS 214-494-2
Isolongifolene
iso-Longifolene
2H-2,4a-Methanonaphthalene, 1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
air; detected; emissions; Europe; Other direct contact consumer goods
IFRA Transparency
Europe
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3183415
Frequently Asked Questions
Is HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE allowed in the EU?
HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE do in cosmetics?
HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 1135-66-6.
Is HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE used outside cosmetics?
HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE have different safety status in cosmetics vs industrial chemicals?
HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE is classified GHS Danger (H304) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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