Hexapeptide-43

INCI: HEXAPEPTIDE-43

CAS Number
| Hexapeptide-40
Function
Humectant, skin conditioning agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not listed as prohibited or restricted in 21 CFR; no CIR monograph

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Hexapeptide-43 is a synthetic peptide permitted for cosmetic use in the EU and US with moderate safety profile and low absorption and sensitization potential.

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Concern Level: Moderate

Frequently Asked Questions

Is Hexapeptide-43 safe in cosmetics?

Hexapeptide-43 is a synthetic peptide permitted for cosmetic use in the EU and US with moderate safety profile and low absorption and sensitization potential. The EU classifies Hexapeptide-43 as "permitted". Safety rating: MODERATE.

Is Hexapeptide-43 allowed in the EU?

Hexapeptide-43 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hexapeptide-43 do in cosmetics?

Hexapeptide-43 functions as: Humectant, skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: | Hexapeptide-40.

What is the Margin of Safety for Hexapeptide-43?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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