Human Amniotic Membrane Stem Cell Conditioned Media

INCI: HUMAN AMNIOTIC MEMBRANE STEM CELL CONDITIONED MEDIA

CAS Number
Not assigned
Function
Skin conditioning, humectant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status prohibited
US Notes Allowed with caveats - conditioned media from human sources can be used in cosmetics provided no drug claims are made; not explicitly prohibited

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Potential FBS (fetal bovine serum) residues if used in culture; pathogen transmission risk from human donor material; batch-to-batch variability; limited standardization. Contains secreted growth factors (HGF, VEGF, IGF-1), cytokines, and ECM proteins from hAECs/hAMSCs; research shows it promotes fibroblast proliferation and reduces senescence markers

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Concern Level: Moderate

Frequently Asked Questions

Is Human Amniotic Membrane Stem Cell Conditioned Media safe in cosmetics?

Potential FBS (fetal bovine serum) residues if used in culture; pathogen transmission risk from human donor material; batch-to-batch variability; limited standardization. Contains secreted growth factors (HGF, VEGF, IGF-1), cytokines, and ECM proteins from hAECs/hAMSCs; research shows it promotes fibroblast proliferation and reduces senescence markers The EU classifies Human Amniotic Membrane Stem Cell Conditioned Media as "prohibited". Safety rating: MODERATE.

Is Human Amniotic Membrane Stem Cell Conditioned Media allowed in the EU?

Human Amniotic Membrane Stem Cell Conditioned Media EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Human Amniotic Membrane Stem Cell Conditioned Media do in cosmetics?

Human Amniotic Membrane Stem Cell Conditioned Media functions as: Skin conditioning, humectant. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Human Amniotic Membrane Stem Cell Conditioned Media?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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