Good Cosmetic Ingredient

Hydrofluorocarbon 227ea

INCI: HYDROFLUOROCARBON 227EA

CAS Number
431-89-0 (1,1,1,2,3,3,3-Heptafluoropropane)
Function
Propellant for aerosol systems
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — listed as acceptable substitute under EPA SNAP program for certain aerosol uses

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Global warming potential of 3,220 is very high among HFC alternatives; environmental regulations are tightening; cosmetic-specific safety data is limited compared to HFC-134a and HFC-152a; cardiac sensitization threshold warrants evaluation for enclosed-space aerosol applications.

⚠️
Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Hydrofluorocarbon 227ea safe in cosmetics?

Global warming potential of 3,220 is very high among HFC alternatives; environmental regulations are tightening; cosmetic-specific safety data is limited compared to HFC-134a and HFC-152a; cardiac sensitization threshold warrants evaluation for enclosed-space aerosol applications. The EU classifies Hydrofluorocarbon 227ea as "permitted". Safety rating: GOOD.

Is Hydrofluorocarbon 227ea allowed in the EU?

Hydrofluorocarbon 227ea EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrofluorocarbon 227ea do in cosmetics?

Hydrofluorocarbon 227ea functions as: Propellant for aerosol systems. It is classified as a cosmetic ingredient in our database. CAS number: 431-89-0 (1,1,1,2,3,3,3-Heptafluoropropane).

What is the Margin of Safety for Hydrofluorocarbon 227ea?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Hydrofluorocarbon 227ea compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

Dipeptide-51
Moderate
Polyurea Crosspolymer-2
Moderate
Sodium Phenoxide
Poor
Barium Gluconate
Poor
Isobutyl Isovalerate
Good
Browse all 30,000+ ingredients →
📱

Is Hydrofluorocarbon 227ea in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Hydrofluorocarbon 227ea in your formulation.

Ingredient Decoder MoS Calculator