Moderate Cosmetic Ingredient NOAEL Data

Hydrogenated Tallowamine

INCI: HYDROGENATED TALLOWAMINE

CAS Number
61788-45-2
Function
Antistatic agent, emulsifier
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR 700

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

6 study endpoints found for Hydrogenated Tallowamine. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 3.25 mg/kg bw/day oral rat oral REACH
NOAEL ca.10 mg/kg bw/day oral rat oral REACH
LOAEL 62.5 other oral rat oral REACH
NOAEL 12.5 other oral rat oral REACH
NOAEL 150 mg/kg bw/day oral rat oral REACH
NOAEL 50 mg/kg bw/day oral rat oral REACH

Expert Verdict

BSE/TSE risk; potential skin/eye irritant at use concentration; N-nitrosamine formation risk (primary amine); ensure hydrogenation is complete to minimize epoxidation-prone unsaturated species; limited CIR standalone data

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Concern Level: Moderate

Frequently Asked Questions

Is Hydrogenated Tallowamine safe in cosmetics?

BSE/TSE risk; potential skin/eye irritant at use concentration; N-nitrosamine formation risk (primary amine); ensure hydrogenation is complete to minimize epoxidation-prone unsaturated species; limited CIR standalone data The EU classifies Hydrogenated Tallowamine as "permitted". Safety rating: MODERATE. 6 toxicological study endpoint(s) are available in our database.

Is Hydrogenated Tallowamine allowed in the EU?

Hydrogenated Tallowamine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrogenated Tallowamine do in cosmetics?

Hydrogenated Tallowamine functions as: Antistatic agent, emulsifier. It is classified as a cosmetic ingredient in our database. CAS number: 61788-45-2.

What is the Margin of Safety for Hydrogenated Tallowamine?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Hydrogenated Tallowamine?

The NOAEL (No Observed Adverse Effect Level) for Hydrogenated Tallowamine is 3.25 mg/kg bw/day based on a oral study via oral route in rat. A total of 6 study endpoints are available. Source: REACH.

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