Hydrogenated Tallowtrimonium Chloride
INCI: HYDROGENATED TALLOWTRIMONIUM CHLORIDE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
8 study endpoints found for Hydrogenated Tallowtrimonium Chloride. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 10 mg/kg bw/day | dermal | code:3484 | dermal | REACH |
| NOEL | ca.100 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 10 mg/kg bw/day | dermal | code:3484 | dermal | REACH |
| NOAEL | ca.113 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 113 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 45 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 100 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 45 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Quaternary ammonium compound with GHS hazard classifications (H314 corrosive, H302 harmful if swallowed, H410 aquatic toxicity); concentration-dependent irritation with typical safety in rinse-off hair products at ≤5%; tallow origin presents BSE/TSE concerns.
Frequently Asked Questions
Is Hydrogenated Tallowtrimonium Chloride safe in cosmetics?
Quaternary ammonium compound with GHS hazard classifications (H314 corrosive, H302 harmful if swallowed, H410 aquatic toxicity); concentration-dependent irritation with typical safety in rinse-off hair products at ≤5%; tallow origin presents BSE/TSE concerns. The EU classifies Hydrogenated Tallowtrimonium Chloride as "permitted". Safety rating: MODERATE. 8 toxicological study endpoint(s) are available in our database.
Is Hydrogenated Tallowtrimonium Chloride allowed in the EU?
Hydrogenated Tallowtrimonium Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydrogenated Tallowtrimonium Chloride do in cosmetics?
Hydrogenated Tallowtrimonium Chloride functions as: Antistatic, hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 61788-78-1.
What is the Margin of Safety for Hydrogenated Tallowtrimonium Chloride?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Hydrogenated Tallowtrimonium Chloride?
The NOAEL (No Observed Adverse Effect Level) for Hydrogenated Tallowtrimonium Chloride is 10 mg/kg bw/day based on a dermal study via dermal route in code:3484. A total of 8 study endpoints are available. Source: REACH.
Compliance Tools
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