Hydrolyzed Casein

INCI: HYDROLYZED CASEIN

CAS Number
65072-00-6 / EC 265-363-1
Function
Hair conditioning, skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” CIR Expert Panel concluded safe as used in cosmetics (reviewed 2022 under bovine milk proteins assessment); used at โ‰ค0.02% max concentration

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Milk allergen; product labeling should warn consumers. Molecular weight should be controlled (restrict to โ‰ค3500 Da per CIR precedent for wheat proteins to avoid systemic sensitization). Cross-reactivity with other dairy proteins is possible.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Hydrolyzed Casein safe in cosmetics?

Milk allergen; product labeling should warn consumers. Molecular weight should be controlled (restrict to โ‰ค3500 Da per CIR precedent for wheat proteins to avoid systemic sensitization). Cross-reactivity with other dairy proteins is possible. The EU classifies Hydrolyzed Casein as "permitted". Safety rating: GOOD.

Is Hydrolyzed Casein allowed in the EU?

Hydrolyzed Casein EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrolyzed Casein do in cosmetics?

Hydrolyzed Casein functions as: Hair conditioning, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 65072-00-6 / EC 265-363-1.

What is the Margin of Safety for Hydrolyzed Casein?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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