Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Silk allergy: rare but documented cases of Type I hypersensitivity to silk proteins exist. Molecular weight of hydrolysate should be characterized — CIR notes MW >3500 Da increases sensitization potential for hydrolyzed proteins generally. Insect-derived (Bombyx mori) — labeling considerations for vegan/ethical claims.
Regulatory Flags
Frequently Asked Questions
Is Hydrolyzed Fibroin safe in cosmetics?
Silk allergy: rare but documented cases of Type I hypersensitivity to silk proteins exist. Molecular weight of hydrolysate should be characterized — CIR notes MW >3500 Da increases sensitization potential for hydrolyzed proteins generally. Insect-derived (Bombyx mori) — labeling considerations for vegan/ethical claims. The EU classifies Hydrolyzed Fibroin as "permitted". Safety rating: GOOD.
Is Hydrolyzed Fibroin allowed in the EU?
Hydrolyzed Fibroin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydrolyzed Fibroin do in cosmetics?
Hydrolyzed Fibroin functions as: Skin conditioning; hair conditioning; humectant. It is classified as a cosmetic ingredient in our database. CAS number: 96690-41-4.
What is the Margin of Safety for Hydrolyzed Fibroin?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Hydrolyzed Fibroin compliance across multiple jurisdictions:
Related Ingredients
Is Hydrolyzed Fibroin in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Hydrolyzed Fibroin in your formulation.