Hydrolyzed Fibronectin

INCI: HYDROLYZED FIBRONECTIN

CAS Number
100085-35-6
Function
Hair conditioning; skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” CIR concluded safe as used in present practices of use and concentration (2017 Final Report on Skin and Connective Tissue-Derived Proteins)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

If bovine-sourced, must comply with 21 CFR ยง700.27 (US) and EC 999/2001 (EU); BSE-free certification required from supplier. If fish-sourced, potential cross-reactivity with fish allergy; source species and tissue must be documented in PIF.

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Concern Level: Moderate

Frequently Asked Questions

Is Hydrolyzed Fibronectin safe in cosmetics?

If bovine-sourced, must comply with 21 CFR ยง700.27 (US) and EC 999/2001 (EU); BSE-free certification required from supplier. If fish-sourced, potential cross-reactivity with fish allergy; source species and tissue must be documented in PIF. The EU classifies Hydrolyzed Fibronectin as "permitted". Safety rating: GOOD.

Is Hydrolyzed Fibronectin allowed in the EU?

Hydrolyzed Fibronectin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrolyzed Fibronectin do in cosmetics?

Hydrolyzed Fibronectin functions as: Hair conditioning; skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 100085-35-6.

What is the Margin of Safety for Hydrolyzed Fibronectin?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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