Hydrolyzed Sericin

INCI: HYDROLYZED SERICIN

CAS Number
60650-89-7 / 60650-88-6 (also reported as 73049-73-7)
Function
Hair conditioning agent, skin conditioning agent, film former, moisturizing agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” CIR Expert Panel concluded safe as used in cosmetics (silk proteins assessment, 2015/2020)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Silk-derived protein with adequate safety profile; CIR Panel approved for cosmetic use. Flag for consumers with known silk allergy as traditional hypersensitivity testing may not detect Type I immediate responses. Limited concentration-of-use data available.

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Concern Level: Low

Frequently Asked Questions

Is Hydrolyzed Sericin safe in cosmetics?

Silk-derived protein with adequate safety profile; CIR Panel approved for cosmetic use. Flag for consumers with known silk allergy as traditional hypersensitivity testing may not detect Type I immediate responses. Limited concentration-of-use data available. The EU classifies Hydrolyzed Sericin as "permitted". Safety rating: GOOD.

Is Hydrolyzed Sericin allowed in the EU?

Hydrolyzed Sericin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrolyzed Sericin do in cosmetics?

Hydrolyzed Sericin functions as: Hair conditioning agent, skin conditioning agent, film former, moisturizing agent. It is classified as a cosmetic ingredient in our database. CAS number: 60650-89-7 / 60650-88-6 (also reported as 73049-73-7).

What is the Margin of Safety for Hydrolyzed Sericin?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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