Moderate Cosmetic Ingredient

Hydrolyzed Serum Protein

INCI: HYDROLYZED SERUM PROTEIN

CAS Number
Not publicly assigned (COSING-listed; no unique CAS for this hydrolysate)
Function
Skin conditioning agent, hair conditioning agent
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status permitted
US Notes Permitted under 21 CFR Parts 700–740. Bovine-derived materials must comply with FDA BSE guidance.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

BSE/TSE risk — must document geographic origin, species, tissue source, and inactivation steps per EU TSE Regulation (EC) 999/2001. Animal-origin ingredients face additional scrutiny in vegan and cruelty-free markets. No CIR monograph available. Not compliant with COSMOS/ECOCERT standards.

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Concern Level: Moderate

Frequently Asked Questions

Is Hydrolyzed Serum Protein safe in cosmetics?

BSE/TSE risk — must document geographic origin, species, tissue source, and inactivation steps per EU TSE Regulation (EC) 999/2001. Animal-origin ingredients face additional scrutiny in vegan and cruelty-free markets. No CIR monograph available. Not compliant with COSMOS/ECOCERT standards. The EU classifies Hydrolyzed Serum Protein as "prohibited". Safety rating: MODERATE.

Is Hydrolyzed Serum Protein allowed in the EU?

Hydrolyzed Serum Protein EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrolyzed Serum Protein do in cosmetics?

Hydrolyzed Serum Protein functions as: Skin conditioning agent, hair conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned (COSING-listed; no unique CAS for this hydrolysate).

What is the Margin of Safety for Hydrolyzed Serum Protein?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Hydrolyzed Serum Protein compliance across multiple jurisdictions:

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Ingredient Decoder
Paste a full ingredient list for instant analysis
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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