Regulatory Status
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Safety Data
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Expert Verdict
IL-4 is an immunomodulatory cytokine; theoretical concern regarding immune suppression at high doses; cosmetic-use levels considered safe
Frequently Asked Questions
Is sh-Polypeptide-12 safe in cosmetics?
IL-4 is an immunomodulatory cytokine; theoretical concern regarding immune suppression at high doses; cosmetic-use levels considered safe The EU classifies sh-Polypeptide-12 as "restricted". Safety rating: GOOD.
Is sh-Polypeptide-12 allowed in the EU?
sh-Polypeptide-12 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does sh-Polypeptide-12 do in cosmetics?
sh-Polypeptide-12 functions as: Skin conditioning, soothing, anti-psoriasis (IL-4 analog — anti-histamine/immune modulator). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned.
What is the Margin of Safety for sh-Polypeptide-12?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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