Withania Somnifera Callus Extract

INCI: WITHANIA SOMNIFERA CALLUS EXTRACT

CAS Number
90147-43-6
Function
Skin conditioning (plant cell culture–derived)
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes Permitted as cosmetic ingredient; no specific FDA monograph; manufacturer bears safety responsibility under FD\&C Act / MoCRA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Callus extracts may contain withanolides; EFSA flagged ashwagandha for safety review in food context (2024) — cosmetic topical use considered lower risk . No CIR final report dedicated to this specific form.

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Concern Level: Low

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Withania Somnifera Callus Extract safe in cosmetics?

Callus extracts may contain withanolides; EFSA flagged ashwagandha for safety review in food context (2024) — cosmetic topical use considered lower risk . No CIR final report dedicated to this specific form. The EU classifies Withania Somnifera Callus Extract as "restricted". Safety rating: GOOD.

Is Withania Somnifera Callus Extract allowed in the EU?

Withania Somnifera Callus Extract EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Withania Somnifera Callus Extract do in cosmetics?

Withania Somnifera Callus Extract functions as: Skin conditioning (plant cell culture–derived). It is classified as a cosmetic ingredient in our database. CAS number: 90147-43-6.

What is the Margin of Safety for Withania Somnifera Callus Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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