Moderate Cosmetic Ingredient

Hydroxyethyl Isostearyloxy Isopropanolamine

INCI: HYDROXYETHYL ISOSTEARYLOXY ISOPROPANOLAMINE

CAS Number
Not widely published — CosIng-listed ingredient without a commonly cited CAS
Function
Emulsifier / conditioning agent (structural class: alkanolamide ether)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted, not in 21 CFR prohibited/restricted lists

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains secondary amine (isopropanolamine) with nitrosamine risk; must not be formulated with nitrosating agents per SCCS guidelines. Maximum recommended NDELA contamination less than 50 ppb in finished product. Requires explicit nitrosamine statement in CPSR.

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Concern Level: Moderate

Frequently Asked Questions

Is Hydroxyethyl Isostearyloxy Isopropanolamine safe in cosmetics?

Contains secondary amine (isopropanolamine) with nitrosamine risk; must not be formulated with nitrosating agents per SCCS guidelines. Maximum recommended NDELA contamination less than 50 ppb in finished product. Requires explicit nitrosamine statement in CPSR. The EU classifies Hydroxyethyl Isostearyloxy Isopropanolamine as "permitted". Safety rating: MODERATE.

Is Hydroxyethyl Isostearyloxy Isopropanolamine allowed in the EU?

Hydroxyethyl Isostearyloxy Isopropanolamine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxyethyl Isostearyloxy Isopropanolamine do in cosmetics?

Hydroxyethyl Isostearyloxy Isopropanolamine functions as: Emulsifier / conditioning agent (structural class: alkanolamide ether). It is classified as a cosmetic ingredient in our database. CAS number: Not widely published — CosIng-listed ingredient without a commonly cited CAS.

What is the Margin of Safety for Hydroxyethyl Isostearyloxy Isopropanolamine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Hydroxyethyl Isostearyloxy Isopropanolamine compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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