Hydroxyethyl Methylthiopropenamide

INCI: HYDROXYETHYL METHYLTHIOPROPENAMIDE

CAS Number
Not confirmed — potentially related to CAS 36585-12-3 but structure mismatch requires verification
Function
Cosmetic ingredient with undocumented specific function
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status prohibited
US Notes Not specifically restricted in 21 CFR prohibited lists; status requires clarification

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Major concern due to propenamide structure analogous to acrylamide (Category 1B mutagen/carcinogen). Genotoxicity clearance and read-across justification required in CPSR before approval.

⚠️
Concern Level: High

Frequently Asked Questions

Is Hydroxyethyl Methylthiopropenamide safe in cosmetics?

Major concern due to propenamide structure analogous to acrylamide (Category 1B mutagen/carcinogen). Genotoxicity clearance and read-across justification required in CPSR before approval. The EU classifies Hydroxyethyl Methylthiopropenamide as "permitted". Safety rating: POOR.

Is Hydroxyethyl Methylthiopropenamide allowed in the EU?

Hydroxyethyl Methylthiopropenamide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxyethyl Methylthiopropenamide do in cosmetics?

Hydroxyethyl Methylthiopropenamide functions as: Cosmetic ingredient with undocumented specific function. It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed — potentially related to CAS 36585-12-3 but structure mismatch requires verification.

What is the Margin of Safety for Hydroxyethyl Methylthiopropenamide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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