Ilex Aquifolium Leaf Extract

INCI: ILEX AQUIFOLIUM LEAF EXTRACT

CAS Number
90045-83-3 [^1_3]
Function
Skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not listed as prohibited or restricted under 21 CFR 700

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Leaf extract is considered safe for topical use despite berries being toxic orally; contains saponins and theobromine; patch testing recommended for sensitive skin.

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Concern Level: Low

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Ilex Aquifolium Leaf Extract safe in cosmetics?

Leaf extract is considered safe for topical use despite berries being toxic orally; contains saponins and theobromine; patch testing recommended for sensitive skin. The EU classifies Ilex Aquifolium Leaf Extract as "permitted". Safety rating: GOOD.

Is Ilex Aquifolium Leaf Extract allowed in the EU?

Ilex Aquifolium Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ilex Aquifolium Leaf Extract do in cosmetics?

Ilex Aquifolium Leaf Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 90045-83-3 [^1_3].

What is the Margin of Safety for Ilex Aquifolium Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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