Isobutylphenoxy Epoxy Resin

INCI: ISOBUTYLPHENOXY EPOXY RESIN

CAS Number
36541-00-1
Function
Film forming (primarily nail products)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” CIR reviewed analogue tosylamide/epoxy resin and concluded safe for nail product use up to 10%

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contact dermatitis is a key concern with documented cases of ectopic allergic contact dermatitis at body parts accessible to wet nails; low MW oligomers may leach from dried film and formaldehyde co-sensitization has been reported. Restrict to nail applications only. HRIPT data on analogue showed safety up to 15% under controlled conditions, but real-world use introduces transfer exposure risk.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Isobutylphenoxy Epoxy Resin safe in cosmetics?

Contact dermatitis is a key concern with documented cases of ectopic allergic contact dermatitis at body parts accessible to wet nails; low MW oligomers may leach from dried film and formaldehyde co-sensitization has been reported. Restrict to nail applications only. HRIPT data on analogue showed safety up to 15% under controlled conditions, but real-world use introduces transfer exposure risk. The EU classifies Isobutylphenoxy Epoxy Resin as "prohibited". Safety rating: MODERATE.

Is Isobutylphenoxy Epoxy Resin allowed in the EU?

Isobutylphenoxy Epoxy Resin EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Isobutylphenoxy Epoxy Resin do in cosmetics?

Isobutylphenoxy Epoxy Resin functions as: Film forming (primarily nail products). It is classified as a cosmetic ingredient in our database. CAS number: 36541-00-1.

What is the Margin of Safety for Isobutylphenoxy Epoxy Resin?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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