Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Isocetyl Stearoyl Stearate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Low-to-moderate comedogenic potential; patch-test advisable for acne-prone skin; no significant toxicological concerns.
Frequently Asked Questions
Is Isocetyl Stearoyl Stearate safe in cosmetics?
Low-to-moderate comedogenic potential; patch-test advisable for acne-prone skin; no significant toxicological concerns. The EU classifies Isocetyl Stearoyl Stearate as "permitted". Safety rating: GOOD. 4 toxicological study endpoint(s) are available in our database.
Is Isocetyl Stearoyl Stearate allowed in the EU?
Isocetyl Stearoyl Stearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isocetyl Stearoyl Stearate do in cosmetics?
Isocetyl Stearoyl Stearate functions as: Emollient, viscosity controlling, pigment dispersant. It is classified as a cosmetic ingredient in our database. CAS number: 97338-28-8.
What is the Margin of Safety for Isocetyl Stearoyl Stearate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Isocetyl Stearoyl Stearate?
The NOAEL (No Observed Adverse Effect Level) for Isocetyl Stearoyl Stearate is >=1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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