Is Isodecyl Alcohol safe in cosmetics?
Isodecyl Alcohol has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.
Isodecyl Alcohol
Also known as: EINECS 246-869-1, UNII-3160X491M7
INCI: ISODECYL ALCOHOL
Isodecyl Alcohol (CAS 25339-17-7) is a cosmetic cosmetic ingredient functioning as Emollient, emulsion stabilizer, viscosity controlling agent. Reported NOAEL =168 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 25339-17-7 →
Auto-generated CPSR Part A draft with source citations
Function
Emollient, emulsion stabilizer, viscosity controlling agent
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
8-methylnonan-1-ol
InChIKey
PLLBRTOLHQQAQQ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — not restricted under 21 CFR
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isodecyl Alcohol.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Isodecyl Alcohol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =168 mg/kg bw/day | oral | Rat | short-term | ToxValDB_ECHA_IUCLID |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract. Exposure could cause depression of the central nervous system.
Long-term Exposure Effects
The substance defats the skin, which may cause dryness or cracking.
Routes of Exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (2)
ICSC Safety Card
0495
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Skin Eye Respiratory Irritation
Direct contact with skin can produce irritation. ... Vapors are non-irritating to the eyes & throat. Causes smarting of skin & first-degree burns on short exposure; may cause secondary burns on long exposure.
Source: Hazardous Substances Data Bank (HSDB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (1)
IFRA Fragrance Transparency List
Expert Verdict
Expert safety assessment and concern-level summary for Isodecyl Alcohol.
Regulatory Flags
potential-allergen
ifra_fragrance
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Isodecyl Alcohol by CAS number or substance name.
Studies
1
Lowest NOAEL
168 mg/kg bw/day
Highest NOAEL
168 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
EINECS 246-869-1
UNII-3160X491M7
Chemical Function
Fragrance
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
IFRA Transparency
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Isodecyl Alcohol allowed in the EU?
Isodecyl Alcohol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isodecyl Alcohol do in cosmetics?
Isodecyl Alcohol functions as: Emollient, emulsion stabilizer, viscosity controlling agent. It is classified as a cosmetic ingredient in our database. CAS number: 25339-17-7.
What is the NOAEL for Isodecyl Alcohol?
The NOAEL (No Observed Adverse Effect Level) for Isodecyl Alcohol is =168 mg/kg bw/day based on a short-term study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.
Is Isodecyl Alcohol used outside cosmetics?
Isodecyl Alcohol also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Isodecyl Alcohol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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