Isopropyl Butyrate

INCI: ISOPROPYL BUTYRATE

CAS Number
638-11-9
Function
Fragrance ingredient
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; FEMA GRAS 2935

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

GHS classifications: skin irritant (Category 2), eye irritant (Category 2A), respiratory irritant (Category 3); flammable (Category 3); maximum fragrance concentrate usage 5.0%; formulate within IFRA limits

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Concern Level: Moderate

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is Isopropyl Butyrate safe in cosmetics?

GHS classifications: skin irritant (Category 2), eye irritant (Category 2A), respiratory irritant (Category 3); flammable (Category 3); maximum fragrance concentrate usage 5.0%; formulate within IFRA limits The EU classifies Isopropyl Butyrate as "permitted". Safety rating: GOOD.

Is Isopropyl Butyrate allowed in the EU?

Isopropyl Butyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isopropyl Butyrate do in cosmetics?

Isopropyl Butyrate functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 638-11-9.

What is the Margin of Safety for Isopropyl Butyrate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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