Isopropyl Cresols

INCI: ISOPROPYL CRESOLS

CAS Number
Mixture of isomers; 4-Isopropyl-m-cresol = 3228-02-2 (also known as O-Cymen-5-ol)
Function
Antimicrobial / preservative / deodorant agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Permitted at concentration โ‰ค0.5%; CIR assessed safe at this level

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Prohibited in EU; restricted in US to โ‰ค0.5% concentration due to toxic effects at higher doses; PCMC restricted in EU and Japan; insufficient data for p-Cresol and mixed cresols.

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

preservative

Frequently Asked Questions

Is Isopropyl Cresols safe in cosmetics?

Prohibited in EU; restricted in US to โ‰ค0.5% concentration due to toxic effects at higher doses; PCMC restricted in EU and Japan; insufficient data for p-Cresol and mixed cresols. The EU classifies Isopropyl Cresols as "prohibited". Safety rating: GOOD.

Is Isopropyl Cresols allowed in the EU?

Isopropyl Cresols EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Isopropyl Cresols do in cosmetics?

Isopropyl Cresols functions as: Antimicrobial / preservative / deodorant agent. It is classified as a cosmetic ingredient in our database. CAS number: Mixture of isomers; 4-Isopropyl-m-cresol = 3228-02-2 (also known as O-Cymen-5-ol).

What is the Margin of Safety for Isopropyl Cresols?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Isopropyl Cresols in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Isopropyl Cresols in your formulation.