Isopropyl Cyanoacrylate

INCI: ISOPROPYL CYANOACRYLATE

CAS Number
10586-17-1
Function
Film former, adhesive for nail adhesive applications
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” listed in FDA GSRS (UNII: I03LI0901Y); on EPA TSCA inventory

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Exothermic polymerization on skin; monomer is an eye and skin irritant; formaldehyde is a degradation byproduct; limited cosmetic-specific toxicological data, primarily studied in medical/surgical adhesive context.

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Concern Level: High

Frequently Asked Questions

Is Isopropyl Cyanoacrylate safe in cosmetics?

Exothermic polymerization on skin; monomer is an eye and skin irritant; formaldehyde is a degradation byproduct; limited cosmetic-specific toxicological data, primarily studied in medical/surgical adhesive context. The EU classifies Isopropyl Cyanoacrylate as "permitted". Safety rating: MODERATE.

Is Isopropyl Cyanoacrylate allowed in the EU?

Isopropyl Cyanoacrylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isopropyl Cyanoacrylate do in cosmetics?

Isopropyl Cyanoacrylate functions as: Film former, adhesive for nail adhesive applications. It is classified as a cosmetic ingredient in our database. CAS number: 10586-17-1.

What is the Margin of Safety for Isopropyl Cyanoacrylate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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