Regulatory Status
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Safety Data
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Expert Verdict
Generally well-tolerated; PCA derivatives are naturally occurring in the skin's NMF (Natural Moisturizing Factor); low irritation and sensitization potential. PCA (pyrrolidone carboxylic acid) is a key component of the skin's NMF; the isopropyl ester form improves lipophilicity and skin penetration compared to sodium PCA, making it useful in emulsion systems where oil-phase humectancy is desired
Regulatory Flags
Frequently Asked Questions
Is Isopropyl PCA safe in cosmetics?
Generally well-tolerated; PCA derivatives are naturally occurring in the skin's NMF (Natural Moisturizing Factor); low irritation and sensitization potential. PCA (pyrrolidone carboxylic acid) is a key component of the skin's NMF; the isopropyl ester form improves lipophilicity and skin penetration compared to sodium PCA, making it useful in emulsion systems where oil-phase humectancy is desired The EU classifies Isopropyl PCA as "permitted". Safety rating: MODERATE.
Is Isopropyl PCA allowed in the EU?
Isopropyl PCA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isopropyl PCA do in cosmetics?
Isopropyl PCA functions as: Humectant; skin conditioning; moisturizer. It is classified as a cosmetic ingredient in our database. CAS number: 68883-70-7.
What is the Margin of Safety for Isopropyl PCA?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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