Is Isoquercetin safe in cosmetics?
Isoquercetin has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Isoquercetin
Also known as: 4-18-00-03493, BRN 0100989, Glucosyl 3-quercetin, 3-Glucosylquercetin, Hirsutrin (+11 more)
INCI: ISOQUERCETIN (APPLIED FOR/REGISTERED UNDER THIS NAME BY MERCK KGAA)
Isoquercetin (CAS 482-35-9) is a cosmetic cosmetic ingredient functioning as Antioxidant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 482-35-9 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
InChIKey
OVSQVDMCBVZWGM-QSOFNFLRSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Allowed - no specific prohibition. Used as a cosmetic active ingredient.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isoquercetin.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
Ceased manufacture
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Expert Verdict
Expert safety assessment and concern-level summary for Isoquercetin.
Known Synonyms
4-18-00-03493
BRN 0100989
Glucosyl 3-quercetin
3-Glucosylquercetin
Hirsutrin
NSC 115918
Quercetin-3-O-glucopyranoside
Quercetin 3-beta-glucoside
Quercetin 3-D-glucoside
Quercetin 3-beta-O-glucoside
Quercetin 3-monoglucoside
Quercetol 3-glucoside
Quercetol 3-monoglucoside
Contigoside B
Isoquercitrin
UNII-6HN2PC637T
Chemical Function
Antioxidant
Regulatory Lists
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
ISOQUERCETIN
ChEMBL ID
CHEMBL250450
Max Phase
2
Frequently Asked Questions
Is Isoquercetin allowed in the EU?
Isoquercetin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isoquercetin do in cosmetics?
Isoquercetin functions as: Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 482-35-9.
Is Isoquercetin used outside cosmetics?
Isoquercetin also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Isoquercetin compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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