Isoquercetin

INCI: ISOQUERCETIN (APPLIED FOR/REGISTERED UNDER THIS NAME BY MERCK KGAA)

CAS Number
482-35-9
Function
Antioxidant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibition. Used as a cosmetic active ingredient.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Generally considered safe for cosmetic use. Merck's Cosmetic Ingredient Dossier confirms suitability for cosmetic formulations without problems.. Quercetin-3-O-glucoside, a plant-derived flavonoid glycoside. More water-soluble than quercetin itself, making it more formulation-friendly. Marketed commercially as RonaCare Isoquercetin. Note: Isoquercetin and isoquercitrin (entry \#6) are the same compound with synonymous names.

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Concern Level: Moderate

Frequently Asked Questions

Is Isoquercetin safe in cosmetics?

Generally considered safe for cosmetic use. Merck's Cosmetic Ingredient Dossier confirms suitability for cosmetic formulations without problems.. Quercetin-3-O-glucoside, a plant-derived flavonoid glycoside. More water-soluble than quercetin itself, making it more formulation-friendly. Marketed commercially as RonaCare Isoquercetin. Note: Isoquercetin and isoquercitrin (entry \#6) are the same compound with synonymous names. The EU classifies Isoquercetin as "permitted". Safety rating: MODERATE.

Is Isoquercetin allowed in the EU?

Isoquercetin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isoquercetin do in cosmetics?

Isoquercetin functions as: Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 482-35-9.

What is the Margin of Safety for Isoquercetin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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