Isostearamidopropyl Morpholine

INCI: ISOSTEARAMIDOPROPYL MORPHOLINE

CAS Number
Not independently well-established (parent amine of CAS 133651-38-4 lactate salt)
Function
Antistatic agent (free base form of the lactate salt)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no CFR prohibition; CIR reviewed only the lactate salt form

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Morpholine is readily nitrosated to form carcinogenic N-nitrosomorpholine; free base is more alkaline and potentially more irritating than lactate salt; CIR data needs for leave-on use remain unfulfilled; this form is rarely used directly—typically neutralized to the lactate salt.

⚠️
Concern Level: High

Frequently Asked Questions

Is Isostearamidopropyl Morpholine safe in cosmetics?

Morpholine is readily nitrosated to form carcinogenic N-nitrosomorpholine; free base is more alkaline and potentially more irritating than lactate salt; CIR data needs for leave-on use remain unfulfilled; this form is rarely used directly—typically neutralized to the lactate salt. The EU classifies Isostearamidopropyl Morpholine as "permitted". Safety rating: MODERATE.

Is Isostearamidopropyl Morpholine allowed in the EU?

Isostearamidopropyl Morpholine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isostearamidopropyl Morpholine do in cosmetics?

Isostearamidopropyl Morpholine functions as: Antistatic agent (free base form of the lactate salt). It is classified as a cosmetic ingredient in our database. CAS number: Not independently well-established (parent amine of CAS 133651-38-4 lactate salt).

What is the Margin of Safety for Isostearamidopropyl Morpholine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

📱

Is Isostearamidopropyl Morpholine in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Isostearamidopropyl Morpholine in your formulation.