Kalanchoe Daigremontiana Leaf Extract

INCI: KALANCHOE DAIGREMONTIANA LEAF EXTRACT

CAS Number
Not assigned
Function
Humectant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not prohibited or restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Bufadienolides (daigremontianin and related compounds) are cardiotoxic; dermal absorption and systemic exposure must be characterized; plant is toxic if ingested and classified poisonous in veterinary literature; lip product use requires extra caution.

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Concern Level: High

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Kalanchoe Daigremontiana Leaf Extract safe in cosmetics?

Bufadienolides (daigremontianin and related compounds) are cardiotoxic; dermal absorption and systemic exposure must be characterized; plant is toxic if ingested and classified poisonous in veterinary literature; lip product use requires extra caution. The EU classifies Kalanchoe Daigremontiana Leaf Extract as "prohibited". Safety rating: MODERATE.

Is Kalanchoe Daigremontiana Leaf Extract allowed in the EU?

Kalanchoe Daigremontiana Leaf Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Kalanchoe Daigremontiana Leaf Extract do in cosmetics?

Kalanchoe Daigremontiana Leaf Extract functions as: Humectant. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Kalanchoe Daigremontiana Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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