Lactobacillus

INCI: LACTOBACILLUS

CAS Number
Not assigned (whole organism genus)
Function
Skin conditioning; antimicrobial (genus-level)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” CIR Expert Panel concluded safe as used (June 2025)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Must be non-viable/inactivated in finished product (live organisms raise preservation and safety concerns); microbial purity per ISO 17516; CIR assessment covers ferment derivatives โ€” confirm whole-organism coverage; endotoxin testing recommended

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Concern Level: Low

Frequently Asked Questions

Is Lactobacillus safe in cosmetics?

Must be non-viable/inactivated in finished product (live organisms raise preservation and safety concerns); microbial purity per ISO 17516; CIR assessment covers ferment derivatives โ€” confirm whole-organism coverage; endotoxin testing recommended The EU classifies Lactobacillus as "restricted". Safety rating: GOOD.

Is Lactobacillus allowed in the EU?

Lactobacillus EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lactobacillus do in cosmetics?

Lactobacillus functions as: Skin conditioning; antimicrobial (genus-level). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (whole organism genus).

What is the Margin of Safety for Lactobacillus?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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