Lactobacillus/Agastache Rugosa Leaf/Stem Extract Ferment Filtrate

INCI: LACTOBACILLUS/AGASTACHE RUGOSA LEAF/STEM EXTRACT FERMENT FILTRATE

CAS Number
Not assigned
Function
Astringent, skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no CFR restriction; CIR read-across applicable

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Estragole (methyl chavicol) is a minor component of Agastache rugosa classified as genotoxic in EU. Fermentation likely reduces volatile content significantly, but analytical confirmation of estragole levels is recommended. Published research supports safety of fermented extract in keratinocyte studies.

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Lactobacillus/Agastache Rugosa Leaf/Stem Extract Ferment Filtrate safe in cosmetics?

Estragole (methyl chavicol) is a minor component of Agastache rugosa classified as genotoxic in EU. Fermentation likely reduces volatile content significantly, but analytical confirmation of estragole levels is recommended. Published research supports safety of fermented extract in keratinocyte studies. The EU classifies Lactobacillus/Agastache Rugosa Leaf/Stem Extract Ferment Filtrate as "permitted". Safety rating: GOOD.

Is Lactobacillus/Agastache Rugosa Leaf/Stem Extract Ferment Filtrate allowed in the EU?

Lactobacillus/Agastache Rugosa Leaf/Stem Extract Ferment Filtrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lactobacillus/Agastache Rugosa Leaf/Stem Extract Ferment Filtrate do in cosmetics?

Lactobacillus/Agastache Rugosa Leaf/Stem Extract Ferment Filtrate functions as: Astringent, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Lactobacillus/Agastache Rugosa Leaf/Stem Extract Ferment Filtrate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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