Is Lanthanum Chloride safe in cosmetics?
Lanthanum Chloride has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.
Lanthanum Chloride
Also known as: Lanthanum chloride (LaCl3), EINECS 233-237-5, UNII-04M8624OXV
INCI: LANTHANUM CHLORIDE
Lanthanum Chloride (CAS 10099-58-8) is a cosmetic cosmetic ingredient functioning as Not assigned a standard cosmetic function in CosIng; used in specialty. Reported NOAEL =40 mg/kg bw/day in Mouse (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 10099-58-8 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Lanthanum Chloride is classified GHS Danger (H290, H315, H317, H318, H319, H335, H411) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Not assigned a standard cosmetic function in CosIng; used in specialty anti-aging research contexts
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
trichlorolanthanum
InChIKey
ICAKDTKJOYSXGC-UHFFFAOYSA-K
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically prohibited; not commonly used in marketed cosmetics
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Lanthanum Chloride.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Lanthanum Chloride. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =40 mg/kg bw/day | oral | Mouse | reproduction developmental | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Astringent
Expert Verdict
Expert safety assessment and concern-level summary for Lanthanum Chloride.
Regulatory Flags
potential-allergen
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Lanthanum Chloride by CAS number or substance name.
Studies
1
Lowest NOAEL
40 mg/kg bw/day
Highest NOAEL
40 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
Lanthanum chloride (LaCl3)
EINECS 233-237-5
UNII-04M8624OXV
Chemical Function
Astringent
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Lanthanum Chloride allowed in the EU?
Lanthanum Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Lanthanum Chloride do in cosmetics?
Lanthanum Chloride functions as: Not assigned a standard cosmetic function in CosIng; used in specialty anti-aging research contexts. It is classified as a cosmetic ingredient in our database. CAS number: 10099-58-8.
What is the NOAEL for Lanthanum Chloride?
The NOAEL (No Observed Adverse Effect Level) for Lanthanum Chloride is =40 mg/kg bw/day based on a reproduction developmental study via oral route in Mouse. Source: ToxValDB_ECHA_IUCLID.
Is Lanthanum Chloride used outside cosmetics?
Lanthanum Chloride also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Lanthanum Chloride have different safety status in cosmetics vs industrial chemicals?
Lanthanum Chloride is classified GHS Danger (H290, H315, H317, H318, H319, H335, H411) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Lanthanum Chloride compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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