Moderate Cosmetic Ingredient NOAEL Data

Lanthanum Chloride

INCI: LANTHANUM CHLORIDE

CAS Number
10099-58-8
Function
Not assigned a standard cosmetic function in CosIng; used in specialty anti-aging research contexts
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically prohibited; not commonly used in marketed cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Lanthanum Chloride. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL >=14000 ppm oral rat oral REACH

Expert Verdict

May cause skin sensitization per SDS data; rare earth metal compounds carry concerns regarding bioaccumulation and environmental persistence; inhalation hazard in powder form. Lanthanum is a rare earth element; chloride salt is water-soluble; some in-vitro research suggests antioxidant-related activity but insufficient cosmetic safety dossier for broad use

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Lanthanum Chloride safe in cosmetics?

May cause skin sensitization per SDS data; rare earth metal compounds carry concerns regarding bioaccumulation and environmental persistence; inhalation hazard in powder form. Lanthanum is a rare earth element; chloride salt is water-soluble; some in-vitro research suggests antioxidant-related activity but insufficient cosmetic safety dossier for broad use The EU classifies Lanthanum Chloride as "permitted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.

Is Lanthanum Chloride allowed in the EU?

Lanthanum Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lanthanum Chloride do in cosmetics?

Lanthanum Chloride functions as: Not assigned a standard cosmetic function in CosIng; used in specialty anti-aging research contexts. It is classified as a cosmetic ingredient in our database. CAS number: 10099-58-8.

What is the Margin of Safety for Lanthanum Chloride?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Lanthanum Chloride?

The NOAEL (No Observed Adverse Effect Level) for Lanthanum Chloride is >=14000 ppm based on a oral study via oral route in rat. Source: REACH.

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