Regulatory Status
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Safety Data
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Expert Verdict
Contains nordihydroguaiaretic acid (NDGA) with documented hepatotoxicity and nephrotoxicity in humans; multiple case reports of liver failure from oral use; banned in several countries as food additive; topical safety data insufficient to establish safe use levels; CPSR submission must address NDGA content quantitatively.
Regulatory Flags
Frequently Asked Questions
Is Larrea Divaricata Extract safe in cosmetics?
Contains nordihydroguaiaretic acid (NDGA) with documented hepatotoxicity and nephrotoxicity in humans; multiple case reports of liver failure from oral use; banned in several countries as food additive; topical safety data insufficient to establish safe use levels; CPSR submission must address NDGA content quantitatively. The EU classifies Larrea Divaricata Extract as "permitted". Safety rating: POOR.
Is Larrea Divaricata Extract allowed in the EU?
Larrea Divaricata Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Larrea Divaricata Extract do in cosmetics?
Larrea Divaricata Extract functions as: Antioxidant, anti-inflammatory, antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 91722-67-7.
What is the Margin of Safety for Larrea Divaricata Extract?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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