Poor Cosmetic Ingredient NOAEL Data

Lauryl Acrylate

INCI: LAURYL ACRYLATE

CAS Number
2156-97-0
Function
Monomer used to synthesize acrylic polymers/copolymers; not typically used as a finished cosmetic ingredient itself
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; not listed under 21 CFR prohibited/restricted substances; governed by general safety requirements under FD&C Act and MoCRA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

4 study endpoints found for Lauryl Acrylate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral - oral REACH
NOAEL 1000 mg/kg bw/day oral - oral REACH

Expert Verdict

Skin irritant and potential skin sensitizer as free monomer; critical concern is residual monomer in polymer/copolymer end-products that must be controlled to trace levels; not appropriate for direct use in leave-on or rinse-off formulations as monomer

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Lauryl Acrylate safe in cosmetics?

Skin irritant and potential skin sensitizer as free monomer; critical concern is residual monomer in polymer/copolymer end-products that must be controlled to trace levels; not appropriate for direct use in leave-on or rinse-off formulations as monomer The EU classifies Lauryl Acrylate as "prohibited". Safety rating: POOR. 4 toxicological study endpoint(s) are available in our database.

Is Lauryl Acrylate allowed in the EU?

Lauryl Acrylate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Lauryl Acrylate do in cosmetics?

Lauryl Acrylate functions as: Monomer used to synthesize acrylic polymers/copolymers; not typically used as a finished cosmetic ingredient itself. It is classified as a cosmetic ingredient in our database. CAS number: 2156-97-0.

What is the Margin of Safety for Lauryl Acrylate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Lauryl Acrylate?

The NOAEL (No Observed Adverse Effect Level) for Lauryl Acrylate is 1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.

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