Good Surfactant NOAEL Data

Lauryl Hydroxysultaine

INCI: LAURYL HYDROXYSULTAINE

CAS Number
13197-76-7
Function
Zwitterionic surfactant, cleansing agent, foam booster, conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR 2024 safe as used, NICNAS 5% leave-on / 10% rinse-off benchmarks

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Lauryl Hydroxysultaine. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 0.5 other oral rat oral REACH

Expert Verdict

Safe zwitterionic surfactant at current use concentrations; does not contain amide susceptible to nitrosation unlike amidopropyl variants; irritating to rabbit eyes at 28-32%.

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Concern Level: Low

Regulatory Flags

epa_safer_alternative

Frequently Asked Questions

Is Lauryl Hydroxysultaine safe in cosmetics?

Safe zwitterionic surfactant at current use concentrations; does not contain amide susceptible to nitrosation unlike amidopropyl variants; irritating to rabbit eyes at 28-32%. The EU classifies Lauryl Hydroxysultaine as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.

Is Lauryl Hydroxysultaine allowed in the EU?

Lauryl Hydroxysultaine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lauryl Hydroxysultaine do in cosmetics?

Lauryl Hydroxysultaine functions as: Zwitterionic surfactant, cleansing agent, foam booster, conditioning. It is classified as a Surfactant in our database. CAS number: 13197-76-7.

What is the Margin of Safety for Lauryl Hydroxysultaine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Lauryl Hydroxysultaine?

The NOAEL (No Observed Adverse Effect Level) for Lauryl Hydroxysultaine is 0.5 other based on a oral study via oral route in rat. Source: REACH.

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