Lithospermum erythrorhizon Root

INCI: LITHOSPERMUM ERYTHRORHIZON ROOT

CAS Number
90045-98-0 / 223749-76-6 [^1_18][^1_19]
Function
Skin conditioning; source of shikonin/alkannin naphthoquinone pigments
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; no specific CFR prohibition. Not a Prop 65-listed substance.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Skin conditioning ingredient sourced for shikonin/alkannin naphthoquinones; may cause eye irritation upon direct contact and can stain due to dark red pigment, with potential interactions at high concentrations on sensitive skin.

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Concern Level: Low

Frequently Asked Questions

Is Lithospermum erythrorhizon Root safe in cosmetics?

Skin conditioning ingredient sourced for shikonin/alkannin naphthoquinones; may cause eye irritation upon direct contact and can stain due to dark red pigment, with potential interactions at high concentrations on sensitive skin. The EU classifies Lithospermum erythrorhizon Root as "permitted". Safety rating: GOOD.

Is Lithospermum erythrorhizon Root allowed in the EU?

Lithospermum erythrorhizon Root EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lithospermum erythrorhizon Root do in cosmetics?

Lithospermum erythrorhizon Root functions as: Skin conditioning; source of shikonin/alkannin naphthoquinone pigments. It is classified as a cosmetic ingredient in our database. CAS number: 90045-98-0 / 223749-76-6 [^1_18][^1_19].

What is the Margin of Safety for Lithospermum erythrorhizon Root?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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