Regulatory Status
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Safety Data
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Expert Verdict
Can cause metabolic acidosis by inhibiting carbonic anhydrase; known to cause pain/burning at application site; potential for hypersensitivity reactions (sulfonamide allergy); not a typical cosmetic ingredient. Molecular formula C₇H₁₁ClN₂O₂S; the hydrochloride salt of mafenide (4-aminomethylbenzenesulfonamide); bacteriostatic against Gram-positive and Gram-negative organisms including Pseudomonas aeruginosa
Frequently Asked Questions
Is Mafenide HCl safe in cosmetics?
Can cause metabolic acidosis by inhibiting carbonic anhydrase; known to cause pain/burning at application site; potential for hypersensitivity reactions (sulfonamide allergy); not a typical cosmetic ingredient. Molecular formula C₇H₁₁ClN₂O₂S; the hydrochloride salt of mafenide (4-aminomethylbenzenesulfonamide); bacteriostatic against Gram-positive and Gram-negative organisms including Pseudomonas aeruginosa The EU classifies Mafenide HCl as "permitted". Safety rating: MODERATE.
Is Mafenide HCl allowed in the EU?
Mafenide HCl EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Mafenide HCl do in cosmetics?
Mafenide HCl functions as: Antimicrobial agent (sulfonamide-type). It is classified as a cosmetic ingredient in our database. CAS number: 138-37-4.
What is the Margin of Safety for Mafenide HCl?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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