Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Magnesium Glycerophosphate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Generally considered safe. Non-toxic at cosmetic use levels; primarily limited to oral care applications.. Provides both magnesium and phosphate ions, which contribute to enamel remineralization. The glycerophosphate moiety is believed to enhance calcium phosphate deposition on tooth surfaces, complementing fluoride in dental formulations.
Regulatory Flags
Frequently Asked Questions
Is Magnesium Glycerophosphate safe in cosmetics?
Generally considered safe. Non-toxic at cosmetic use levels; primarily limited to oral care applications.. Provides both magnesium and phosphate ions, which contribute to enamel remineralization. The glycerophosphate moiety is believed to enhance calcium phosphate deposition on tooth surfaces, complementing fluoride in dental formulations. The EU classifies Magnesium Glycerophosphate as "permitted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.
Is Magnesium Glycerophosphate allowed in the EU?
Magnesium Glycerophosphate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Magnesium Glycerophosphate do in cosmetics?
Magnesium Glycerophosphate functions as: Oral care. It is classified as a cosmetic ingredient in our database. CAS number: 927-20-8.
What is the Margin of Safety for Magnesium Glycerophosphate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Magnesium Glycerophosphate?
The NOAEL (No Observed Adverse Effect Level) for Magnesium Glycerophosphate is >=1000 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.
Compliance Tools
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Related Ingredients
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