MEA-Sulfite

INCI: MEA-SULFITE

CAS Number
13427-63-9
Function
Hair fixative (used in permanent waving/hair straightening processes)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed; CIR found safe in rinse-off products when formulated to be non-irritating and not used where N-nitroso compounds may form

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Nitrosamine formation; sulfite sensitivity (particularly in asthmatics); potential skin/eye irritation. Inorganic acid salt of ethanolamine; the sulfite moiety acts as a mild reducing agent that breaks disulfide bonds in hair keratin, enabling reshaping; milder than thioglycolate-based systems

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Concern Level: Moderate

Frequently Asked Questions

Is MEA-Sulfite safe in cosmetics?

Nitrosamine formation; sulfite sensitivity (particularly in asthmatics); potential skin/eye irritation. Inorganic acid salt of ethanolamine; the sulfite moiety acts as a mild reducing agent that breaks disulfide bonds in hair keratin, enabling reshaping; milder than thioglycolate-based systems The EU classifies MEA-Sulfite as "restricted". Safety rating: MODERATE.

Is MEA-Sulfite allowed in the EU?

MEA-Sulfite EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does MEA-Sulfite do in cosmetics?

MEA-Sulfite functions as: Hair fixative (used in permanent waving/hair straightening processes). It is classified as a cosmetic ingredient in our database. CAS number: 13427-63-9.

What is the Margin of Safety for MEA-Sulfite?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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