Melia Azadirachta Branch/Leaf Extract

INCI: MELIA AZADIRACHTA BRANCH/LEAF EXTRACT

CAS Number
84696-25-3 / 90063-92-6
Function
Skin protecting
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not prohibited or restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Neem extracts can cause contact dermatitis in sensitive individuals; oral toxicity of neem compounds (azadirachtin) is well-documented - topical cosmetic use at typical levels is generally considered safe. Derived from the Neem Tree (Azadirachta indica, syn. Melia azadirachta); branch and leaf combination provides broad-spectrum bioactives including nimbin and nimbidin with documented anti-inflammatory and antimicrobial activity

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Melia Azadirachta Branch/Leaf Extract safe in cosmetics?

Neem extracts can cause contact dermatitis in sensitive individuals; oral toxicity of neem compounds (azadirachtin) is well-documented - topical cosmetic use at typical levels is generally considered safe. Derived from the Neem Tree (Azadirachta indica, syn. Melia azadirachta); branch and leaf combination provides broad-spectrum bioactives including nimbin and nimbidin with documented anti-inflammatory and antimicrobial activity The EU classifies Melia Azadirachta Branch/Leaf Extract as "permitted". Safety rating: MODERATE.

Is Melia Azadirachta Branch/Leaf Extract allowed in the EU?

Melia Azadirachta Branch/Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Melia Azadirachta Branch/Leaf Extract do in cosmetics?

Melia Azadirachta Branch/Leaf Extract functions as: Skin protecting. It is classified as a cosmetic ingredient in our database. CAS number: 84696-25-3 / 90063-92-6.

What is the Margin of Safety for Melia Azadirachta Branch/Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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