Methoxy PEG-100 Propyl Melittin Amide

INCI: METHOXY PEG-100 PROPYL MELITTIN AMIDE

CAS Number
Not publicly assigned.
Function
Anti-seborrhoeic - prevents or relieves excessive sebum secretion.
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed; not specifically prohibited or restricted.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Melittin is the principal active peptide in bee venom, known for its membrane-disrupting, anti-inflammatory, and antimicrobial properties. The PEGylated amide conjugate is designed to moderate melittin's cytotoxicity. Potential for skin sensitization in individuals with bee venom allergy. Limited published safety data for this specific conjugate.. PEGylated bee venom peptide derivative; the PEG-100 chain is intended to improve solubility, reduce toxicity, and enhance stability of the melittin...

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Concern Level: High

Regulatory Flags

potential-allergen peg-ingredient

Frequently Asked Questions

Is Methoxy PEG-100 Propyl Melittin Amide safe in cosmetics?

Melittin is the principal active peptide in bee venom, known for its membrane-disrupting, anti-inflammatory, and antimicrobial properties. The PEGylated amide conjugate is designed to moderate melittin's cytotoxicity. Potential for skin sensitization in individuals with bee venom allergy. Limited published safety data for this specific conjugate.. PEGylated bee venom peptide derivative; the PEG-100 chain is intended to improve solubility, reduce toxicity, and enhance stability of the melittin... The EU classifies Methoxy PEG-100 Propyl Melittin Amide as "permitted". Safety rating: MODERATE.

Is Methoxy PEG-100 Propyl Melittin Amide allowed in the EU?

Methoxy PEG-100 Propyl Melittin Amide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methoxy PEG-100 Propyl Melittin Amide do in cosmetics?

Methoxy PEG-100 Propyl Melittin Amide functions as: Anti-seborrhoeic - prevents or relieves excessive sebum secretion.. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned..

What is the Margin of Safety for Methoxy PEG-100 Propyl Melittin Amide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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