Methoxy PEG-144

INCI: METHOXY PEG-144

CAS Number
9004-74-4 (generic methoxy polyethylene glycol)
Function
Not yet formally assigned by CosIng; based on PEG class behavior at this molecular weight (~6,340 g/mol), it functions as a consistency enhancer and humectant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - PEGs are permitted cosmetic ingredients; no specific FDA prohibition

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

General PEG class concerns include potential 1,4-dioxane and ethylene oxide contamination from manufacturing; may enhance penetration of other ingredients through compromised skin. Solid waxy consistency (PEGs above ~4,000 g/mol are solid); water-soluble, non-greasy; decreasing hygroscopicity with increasing molecular weight

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

peg-ingredient

Frequently Asked Questions

Is Methoxy PEG-144 safe in cosmetics?

General PEG class concerns include potential 1,4-dioxane and ethylene oxide contamination from manufacturing; may enhance penetration of other ingredients through compromised skin. Solid waxy consistency (PEGs above ~4,000 g/mol are solid); water-soluble, non-greasy; decreasing hygroscopicity with increasing molecular weight The EU classifies Methoxy PEG-144 as "permitted". Safety rating: MODERATE.

Is Methoxy PEG-144 allowed in the EU?

Methoxy PEG-144 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methoxy PEG-144 do in cosmetics?

Methoxy PEG-144 functions as: Not yet formally assigned by CosIng; based on PEG class behavior at this molecular weight (~6,340 g/mol), it functions as a consistency enhancer and humectant. It is classified as a cosmetic ingredient in our database. CAS number: 9004-74-4 (generic methoxy polyethylene glycol).

What is the Margin of Safety for Methoxy PEG-144?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Methoxy PEG-144 in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Methoxy PEG-144 in your formulation.