Regulatory Status
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Safety Data
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Expert Verdict
Causes severe photosensitivity - skin treated with this compound becomes extremely sensitive to light and can develop phototoxic reactions (erythema, burning, blistering). Strictly for controlled clinical/professional use. Prodrug - metabolized intracellularly to protoporphyrin IX (PpIX), which is a potent photosensitizer. When exposed to specific wavelength light, PpIX generates reactive oxygen species that destroy targeted cells
Frequently Asked Questions
Is Methyl Aminolevulinate HCl safe in cosmetics?
Causes severe photosensitivity - skin treated with this compound becomes extremely sensitive to light and can develop phototoxic reactions (erythema, burning, blistering). Strictly for controlled clinical/professional use. Prodrug - metabolized intracellularly to protoporphyrin IX (PpIX), which is a potent photosensitizer. When exposed to specific wavelength light, PpIX generates reactive oxygen species that destroy targeted cells The EU classifies Methyl Aminolevulinate HCl as "permitted". Safety rating: MODERATE.
Is Methyl Aminolevulinate HCl allowed in the EU?
Methyl Aminolevulinate HCl EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Methyl Aminolevulinate HCl do in cosmetics?
Methyl Aminolevulinate HCl functions as: Listed in CosIng as a cosmetic ingredient; however, its primary real-world use is pharmaceutical - as a photosensitizer in photodynamic therapy (PDT). It is classified as a cosmetic ingredient in our database. CAS number: 79416-27-6.
What is the Margin of Safety for Methyl Aminolevulinate HCl?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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