Methyl Bimatoprost Acidate

INCI: METHYL BIMATOPROST ACIDATE

CAS Number
38315-47-8
Function
Eyelash conditioning agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not prohibited as a cosmetic ingredient per se - FDA confirmed that without drug claims, prostaglandin-containing products may be classified as cosmetics; however, bimatoprost itself (the parent) is an FDA-approved prescription drug (Latisse)

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Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Serious - prostaglandin analogue with potent pharmacological activity at very low concentrations; reported adverse effects include: iris color change (irreversible), periorbital fat atrophy, eyelid hyperpigmentation, conjunctival hyperemia, eye irritation. Synthetic prostaglandin Fโ‚‚ฮฑ analogue; frequency of use: not reported (FOU NR) in US VCRP ; structurally related to bimatoprost; the SCCS opinion covers 19 prostaglandin analogues including this one

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Concern Level: Moderate

Frequently Asked Questions

Is Methyl Bimatoprost Acidate safe in cosmetics?

Serious - prostaglandin analogue with potent pharmacological activity at very low concentrations; reported adverse effects include: iris color change (irreversible), periorbital fat atrophy, eyelid hyperpigmentation, conjunctival hyperemia, eye irritation. Synthetic prostaglandin Fโ‚‚ฮฑ analogue; frequency of use: not reported (FOU NR) in US VCRP ; structurally related to bimatoprost; the SCCS opinion covers 19 prostaglandin analogues including this one The EU classifies Methyl Bimatoprost Acidate as "permitted". Safety rating: MODERATE.

Is Methyl Bimatoprost Acidate allowed in the EU?

Methyl Bimatoprost Acidate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methyl Bimatoprost Acidate do in cosmetics?

Methyl Bimatoprost Acidate functions as: Eyelash conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 38315-47-8.

What is the Margin of Safety for Methyl Bimatoprost Acidate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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