Methyl Ethylacetoacetate

INCI: METHYL ETHYLACETOACETATE

CAS Number
51756-08-2
Function
Perfuming agent
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status permitted
US Notes Allowed - not listed as a prohibited or restricted cosmetic ingredient. RIFM (Research Institute for Fragrance Materials) has assessed it with a calculated Margin of Exposure (MOE) > 100 for repeated-dose and reproductive toxicity endpoints.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Low concern at declared use levels. Sensitization potential has been evaluated and cleared at screening level.. Molecular weight 144.17; density ~1.010 g/mL; boiling point ~262°C. Primarily a fragrance building block rather than an active functional ingredient.

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is Methyl Ethylacetoacetate safe in cosmetics?

Low concern at declared use levels. Sensitization potential has been evaluated and cleared at screening level.. Molecular weight 144.17; density ~1.010 g/mL; boiling point ~262°C. Primarily a fragrance building block rather than an active functional ingredient. The EU classifies Methyl Ethylacetoacetate as "prohibited". Safety rating: MODERATE.

Is Methyl Ethylacetoacetate allowed in the EU?

Methyl Ethylacetoacetate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Methyl Ethylacetoacetate do in cosmetics?

Methyl Ethylacetoacetate functions as: Perfuming agent. It is classified as a cosmetic ingredient in our database. CAS number: 51756-08-2.

What is the Margin of Safety for Methyl Ethylacetoacetate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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