Isoamyl Butyrate

INCI: ISOAMYL BUTYRATE

CAS Number
106-27-4 [^1_1]
Function
Fragrance ingredient
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — GRAS flavoring (21 CFR 172.515); not prohibited under 21 CFR 700 for cosmetic use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Flammable liquid; Cramer Class I with no genotoxicity or reproductive toxicity concerns.

⚠️
Concern Level: Low

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is Isoamyl Butyrate safe in cosmetics?

Flammable liquid; Cramer Class I with no genotoxicity or reproductive toxicity concerns. The EU classifies Isoamyl Butyrate as "permitted". Safety rating: GOOD.

Is Isoamyl Butyrate allowed in the EU?

Isoamyl Butyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isoamyl Butyrate do in cosmetics?

Isoamyl Butyrate functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 106-27-4 [^1_1].

What is the Margin of Safety for Isoamyl Butyrate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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