Methyl Morpholine Oxide

INCI: METHYL MORPHOLINE OXIDE

CAS Number
7529-22-8
Function
Surfactant; industrial solvent and cellulose-dissolving agent
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR cosmetic prohibition, but no FDA GRAS or CIR review for cosmetic use identified

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

GHS-classified skin and eye irritant (H315, H319) and respiratory irritant (H335). Primarily an industrial chemical with marginal cosmetic use. No CIR, SCCS, or RIFM safety assessment identified for cosmetic application. Oxidizing amine N-oxide may be incompatible with certain cosmetic actives. Not recommended without full toxicological dossier.

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Concern Level: High

Frequently Asked Questions

Is Methyl Morpholine Oxide safe in cosmetics?

GHS-classified skin and eye irritant (H315, H319) and respiratory irritant (H335). Primarily an industrial chemical with marginal cosmetic use. No CIR, SCCS, or RIFM safety assessment identified for cosmetic application. Oxidizing amine N-oxide may be incompatible with certain cosmetic actives. Not recommended without full toxicological dossier. The EU classifies Methyl Morpholine Oxide as "permitted". Safety rating: POOR.

Is Methyl Morpholine Oxide allowed in the EU?

Methyl Morpholine Oxide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methyl Morpholine Oxide do in cosmetics?

Methyl Morpholine Oxide functions as: Surfactant; industrial solvent and cellulose-dissolving agent. It is classified as a cosmetic ingredient in our database. CAS number: 7529-22-8.

What is the Margin of Safety for Methyl Morpholine Oxide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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