Moderate Cosmetic Ingredient NOAEL Data

TEA-Cocoyl Sarcosinate

INCI: TEA-COCOYL SARCOSINATE

CAS Number
68411-97-2
Function
Surfactant – Cleansing, Foaming, Emulsifying
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes Permitted; CIR: safe as used when formulated to be non-irritating

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

3 study endpoints found for TEA-Cocoyl Sarcosinate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL >=2 other oral rat oral REACH
LOAEL 100 mg/kg bw/day oral rat oral REACH
NOAEL >=2 other oral - oral REACH

Expert Verdict

HIGHEST nitrosamine risk in this group – sarcosine is itself a secondary amine (N-methylglycine); NDELA (N-nitrosodiethanolamine) formation must be actively monitored; requires rigorous nitrosamine testing; must not use with nitrosating agents

⚠️
Concern Level: Moderate

Regulatory Flags

epa_safer_alternative

Frequently Asked Questions

Is TEA-Cocoyl Sarcosinate safe in cosmetics?

HIGHEST nitrosamine risk in this group – sarcosine is itself a secondary amine (N-methylglycine); NDELA (N-nitrosodiethanolamine) formation must be actively monitored; requires rigorous nitrosamine testing; must not use with nitrosating agents The EU classifies TEA-Cocoyl Sarcosinate as "restricted". Safety rating: MODERATE. 3 toxicological study endpoint(s) are available in our database.

Is TEA-Cocoyl Sarcosinate allowed in the EU?

TEA-Cocoyl Sarcosinate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does TEA-Cocoyl Sarcosinate do in cosmetics?

TEA-Cocoyl Sarcosinate functions as: Surfactant – Cleansing, Foaming, Emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 68411-97-2.

What is the Margin of Safety for TEA-Cocoyl Sarcosinate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for TEA-Cocoyl Sarcosinate?

The NOAEL (No Observed Adverse Effect Level) for TEA-Cocoyl Sarcosinate is >=2 other based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.

📱

Is TEA-Cocoyl Sarcosinate in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for TEA-Cocoyl Sarcosinate in your formulation.