Regulatory Status
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Safety Data
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Expert Verdict
L-Tryptophan supplements were historically associated with eosinophilia-myalgia syndrome (EMS) due to contaminated batches in the late 1980s; however, the methyl ester HCl salt for topical cosmetic use is considered low risk. Standard irritation testing recommended.. White to light yellow/orange powder or crystal; L-tryptophan methyl ester hydrochloride; amino acid ester that can enhance skin penetration of active compounds.
Frequently Asked Questions
Is Methyl Tryptophanate HCl safe in cosmetics?
L-Tryptophan supplements were historically associated with eosinophilia-myalgia syndrome (EMS) due to contaminated batches in the late 1980s; however, the methyl ester HCl salt for topical cosmetic use is considered low risk. Standard irritation testing recommended.. White to light yellow/orange powder or crystal; L-tryptophan methyl ester hydrochloride; amino acid ester that can enhance skin penetration of active compounds. The EU classifies Methyl Tryptophanate HCl as "permitted". Safety rating: MODERATE.
Is Methyl Tryptophanate HCl allowed in the EU?
Methyl Tryptophanate HCl EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Methyl Tryptophanate HCl do in cosmetics?
Methyl Tryptophanate HCl functions as: Skin conditioning / hair conditioning agent (amino acid derivative). It is classified as a cosmetic ingredient in our database. CAS number: 7524-52-9.
What is the Margin of Safety for Methyl Tryptophanate HCl?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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