Good Cosmetic Ingredient NOAEL Data

Theobroma Cacao Seed Powder

INCI: THEOBROMA CACAO SEED POWDER

CAS Number
84649-99-0
Function
Abrasive, Skin Conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted for cosmetic use; covered under CIR plant-derived fatty acid oils group assessment

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Theobroma Cacao Seed Powder. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 4280 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 2140 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB

Expert Verdict

Over-exfoliation risk with aggressive particle size; ensure milling specifications for cosmetic-grade particle uniformity; potential inhalation concern in powder handling (GMP)

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Concern Level: Low

Regulatory Flags

fda_food_additive

Frequently Asked Questions

Is Theobroma Cacao Seed Powder safe in cosmetics?

Over-exfoliation risk with aggressive particle size; ensure milling specifications for cosmetic-grade particle uniformity; potential inhalation concern in powder handling (GMP) The EU classifies Theobroma Cacao Seed Powder as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is Theobroma Cacao Seed Powder allowed in the EU?

Theobroma Cacao Seed Powder EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Theobroma Cacao Seed Powder do in cosmetics?

Theobroma Cacao Seed Powder functions as: Abrasive, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84649-99-0.

What is the Margin of Safety for Theobroma Cacao Seed Powder?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Theobroma Cacao Seed Powder?

The NOAEL (No Observed Adverse Effect Level) for Theobroma Cacao Seed Powder is 4280 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

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