Methyl Vanillate

INCI: METHYL VANILLATE

CAS Number
3943-74-6
Function
Fragrance (perfuming)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not on prohibited or restricted lists; has RIFM safety assessment supporting safe use in fragrances

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

RIFM Expert Panel concluded the material is safe as described in their assessment; not classified as PBT or vPvB under EU REACH screening criteria. Methyl ester of vanillic acid (4-hydroxy-3-methoxybenzoic acid); provides a soft vanilla/sweet aromatic character

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Concern Level: Moderate

Regulatory Flags

fragrance-component ifra_fragrance

Frequently Asked Questions

Is Methyl Vanillate safe in cosmetics?

RIFM Expert Panel concluded the material is safe as described in their assessment; not classified as PBT or vPvB under EU REACH screening criteria. Methyl ester of vanillic acid (4-hydroxy-3-methoxybenzoic acid); provides a soft vanilla/sweet aromatic character The EU classifies Methyl Vanillate as "permitted". Safety rating: MODERATE.

Is Methyl Vanillate allowed in the EU?

Methyl Vanillate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methyl Vanillate do in cosmetics?

Methyl Vanillate functions as: Fragrance (perfuming). It is classified as a cosmetic ingredient in our database. CAS number: 3943-74-6.

What is the Margin of Safety for Methyl Vanillate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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